What Can Cause Sudden Confusion or Weakness in an Older Adult?

Older man with his hand on his forehead looking confused while checking his watch

Sudden confusion or weakness in seniors should be treated as a new medical problem – not dismissed as just “normal aging.” Confusion that develops over hours or days is often called delirium. It may involve poor attention, disorientation, disorganized speech, unusual sleepiness, agitation, hallucinations, or rapidly changing alertness. Unlike dementia – which usually progresses gradually, delirium begins abruptly and often fluctuates during the day. It may be reversible, but the underlying cause can be life-threatening.

Stroke or transient ischemic attack

Stroke is one of the most urgent causes of sudden weakness or confusion. Warning signs include:

  • Abrupt weakness or numbness of the face, arm or leg – usually on one side
  • Facial drooping
  • Slurred or unusual speech
  • Difficulty understanding language
  • Vision changes
  • Loss of balance
  • Dizziness
  • Severe unexplained headache

A good way to help remember? Use B.E.F.A.S.T.:

  • Balance loss
  • Eye changes
  • Face drooping
  • Arm weakness
  • Speech difficulty
  • Time to call 911

Call 911 immediately for any possible stroke, even if symptoms are mild or disappear after several minutes. Brief symptoms may represent a transient ischemic attack, sometimes called a “mini-stroke”, which still requires emergency evaluation. Note the time the person was last known to be normal. Do not drive the person to the hospital – emergency personnel can begin care during transport and alert the hospital in advance.

Infection and sepsis

Urinary, lung, skin, abdominal, and other infections commonly precipitate delirium in older adults. An older person may develop confusion, weakness, reduced mobility, poor appetite, or unusual sleepiness before displaying typical symptoms. Some older adults with serious infection may not develop a prominent fever.

Sepsis is the body’s extreme response to infection and is a medical emergency. Warning signs include:

  • New confusion or disorientation
  • Fever
  • Shivering or feeling unusually cold, clammy skin
  • Rapid heart rate or weak pulse
  • Shortness of breath
  • Extreme pain or discomfort

Call 911 when sudden confusion occurs with these signs or when the person appears severely ill or is deteriorating quickly.

Medication effects

New medicines, dosage changes, medication interactions, accidental double doses, or abrupt withdrawal can cause confusion and weakness. Higher-risk categories include opioids, sedatives, benzodiazepines, antihistamines, and medicines with anticholinergic effects. Alcohol or other substances can also cause intoxication or withdrawal delirium. Older adults may be especially sensitive because medications can remain in their bodies longer or interact with multiple prescriptions.

Low blood sugar

Hypoglycemia can develop rapidly, particularly in someone taking insulin or certain diabetes medicines. Symptoms may include:

  • Weakness
  • Fatigue
  • Dizziness
  • Sweating
  • Trembling
  • Irritability
  • Confusion
  • Blurred vision
  • Difficulty speaking
  • Seizure
  • Unconsciousness

Older adults may display confusion or weakness without the more familiar warning signs of shaking or hunger.

If possible, check the person’s glucose and follow their prescribed hypoglycemic plan. An alert person who can swallow safely may be given the recommended fast-acting carbohydrate. Never give food or drink to someone who is drowsy, unconscious, seizing, or unable to swallow safely. Use prescribed glucagon if trained to do so, and call 911 for severe symptoms, unconsciousness, seizure, inability to swallow, or failure to improve after treatment.

Dehydration and metabolic disturbances

Dehydration, abnormal sodium or other electrolyte levels, kidney or liver failure, thyroid disorders, nutritional deficiencies, and low oxygen can impair brain function and produce generalized weakness. Warning clues include:

  • Vomiting
  • Diarrhea
  • Fever
  • Poor fluid intake
  • Excessive urination
  • Use of diuretics
  • Reduced urine output
  • Dizziness
  • Dry mouth
  • Rapid pulse
  • Increasing sleepiness

Severe dehydration accompanied by confusion or a change in alertness requires urgent medical attention.

Falls and head injury

A fall or head impact can cause concussion or bleeding around the brain. Symptoms may not appear immediately, and the injured person may not remember falling. Confusion, worsening headache, repeated vomiting, unusual sleepiness, slurred speech, poor coordination, seizure, or new arm or leg weakness requires emergency evaluation. This is especially important when the person takes a blood thinner.

When to call 911

Call 911 for:

  • Sudden unexplained confusion
  • Suspected stroke
  • Inability to awaken
  • Seizure
  • Fainting
  • New one-sided weakness
  • Inability to speak or walk
  • Serious breathing difficulty
  • Chest pain
  • Severe headache
  • Confusion following a head injury
  • Signs of sepsis

Stay with the person, prevent falls, and do NOT give food, drink or medication unless it’s safe and specifically indicated. Record when symptoms began and bring the medication list, medical history, allergies, and advance directives if readily available.

Even when no 911 warning sign is present, a rapid change from the person’s usual mental or physical function warrants prompt same-day medical assessment. Dementia does not protect someone from delirium – both can occur together, and a sudden change usually indicates an additional illness or injury that needs evaluation.

Sources:
National Institute on Aging
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
MedlinePlus
Centers for Disease Control and Prevention (CDC)

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